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TGR Enzymatic Assays Assays were performed at 25 C in 0.1 M potassium phosphate (pH 7.4), 10 mM EDTA using 100 M NADPH unless otherwise stated

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Strikingly, simply increasing mitochondrial GSH levels by expressing mito-GSHf in SLC25A39/40 double knockout cells completely restored the reduced levels of mitochondrial translation machinery proteins, iron-sulfur containing proteins, and aconitase activity (Fig 4f,g)

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Glutathione can also make skin look brighter and more radiant by reducing melanin production