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Abbreviations AKI: Acute Kidney Injury BMI: Body Mass Index VAS: Visual Analog Scale SD: Standard Deviation IQR: Interquartile range CoA: Coenzyme A NF-B: Nuclear factor-kappa B IGF-1: Insulin-like Growth Factor 1 MAFLD: Metabolic Dysfunction-Associated Fatty Liver Disease References Konikoff F, Theodor E

Ultimately, this FOXO4-DRI-mediated mechanism selectively eliminates senescent endothelial cells, which in turn attenuates vascular inflammation and improves endothelial-dependent vasodilation, conferring a significant protective effect on vascular function