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Increased levels of alkyl hydroperoxide reductase AhpC/AhpF inactivate OxyR induced transcription by removing the signal molecule H 2 O 2
As mentioned above, several immune cells and inflammatory mediators seem to have a dual role in aggravating liver damage and promoting liver repair and regeneration, which, to some extent, affects scientists to translate this knowledge into effective treatment of AILI (with NAC being still the only FDA approved antidote)
& Kamp, D
J Inherit.Metab Dis 2007;30(5):811
