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Responses to the open-ended question were analyzed using thematic analysis

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4.2.4 Targeting necroptosis in CP-induced AKI Given the central role of the necroptotic pathway and its associated inflammation in the pathogenesis of CP-induced AKI along with their potential role in AKI-to-CKD transition, multiple agents with anti-necroptotic activity were tested in the CP-induced AKI model

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Discuss with your endocrinologist If you have a seizure history: high-dose L-carnitine has been associated with increased seizure frequency in susceptible individuals in rare reports A 2013 Cleveland Clinic study raised concern about gut bacteria converting L-carnitine to TMAO (trimethylamine N-oxide), a compound associated with cardiovascular risk

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Individuals who smoked cigarettes showed significantly greater reductions in cigarettes per day when receiving semaglutide compared to the placebo group 22

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