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They directly impact psychiatric disease states

People with stomach and intestinal conditions such as celiac disease and Crohns disease may struggle to absorb enough B12 from their food

Wegovy is approved to reduce the risk of serious cardiovascular events like heart attack and stroke in adults with cardiovascular disease, MASH, and either obesity or overweight and Zepbound is approved for treating moderate-to-severe obstructive sleep apnea in adults with obesity

With respect to the previously mentioned study, this proof-of concept study has important methodological strengths residing in the availability of baseline and post-treatment hepatic biopsies