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This substudy was required by the FDA to ensure the drug did not cause excessive HR increase and included 600 patients who underwent ABPM prior to randomization and again at the end of the 36-week study period

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The honest summary: strong mechanistic and animal evidence, essentially no completed human efficacy trials

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Lifestyle, exercise, and nutrition support

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Vaccines at $0: As of 2023, all adult vaccines recommended by ACIP and covered under Part D must be provided with no cost-sharing

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