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Risk factors include age (usually affects people over 50), diabetes, hypertension, high cholesterol, sleep apnea, and anatomical predispositions such as a small cup-to-disc ratio

Increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes, especially those who also take medicines for type 2 diabetes such as sulfonylureas or insulin

While the vial contains 60mg total, it is imperative that healthcare professionals adhere to the established, safe, and effective weekly dosing protocols

In women, occasional reports involve decreased libido or menstrual irregularities, but strong clinical evidence is lacking