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Others may be advised to temporarily hold the medication, follow a clear liquid diet before surgery, or delay an elective procedure until gastrointestinal symptoms improve

Ensure adequate magnesium intake through dark leafy greens, nuts, seeds, or supplementation with 200-400mg of magnesium glycinate daily, a form particularly beneficial for anxiety

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It enhances both insulinotropic and glucagonostatic actions more robustly

Thus, by addressing barriers that can be alleviated by orforglipron, generating evidence of its ability to maintain body weight reduction, along with safety data when switching to oral therapy, can help advance the field of obesity medicine