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Here are some of the most common contraindications for semaglutide for weight loss: History of thyroid cancer: Semaglutide has been shown to cause thyroid tumors in animals, and therefore, it is not recommended for individuals with a history of thyroid cancer or those with a family history of medullary thyroid carcinoma (MTC)

Simultaneous angiotensin receptor blockade and glucagon-like peptide-1 receptor activation ameliorate albuminuria in obese insulin-resistant rats

They may also use body mass index (BMI) to help decide if semaglutide may be an option

In 2022, GLP-1 drugs became available as weight management drugs

It is not a pharmacogenomic test and never predicts response to any specific dose or medication