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Lancet 2018;392:151929.PubMed 70
As before, LIRA caused greater weight loss in Gipr hypo-KO than in Gipr hypo-GFP mice, and LIRA + GIPR-antag caused more weight loss than LIRA alone in the control Gipr hypo-GFP group (Fig
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Clinical trials combining these agents reported 35-40% discontinuation rates when both were dosed together
