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Keywords: tumor resistance, glutathione S -transferase pi, drug treatment Introduction In addition to combating a variety of noxious substances from the external environment, cell-detoxification mechanisms are capable of resisting the deleterious effects of certain endogenous substances (eg, ROS, a product generated from normal cellular metabolism), in order to maintain physiological homeostasis

The therapy may support various functions such as detoxification, promoting healthy skin, and assisting with cellular repair

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Initially, we determined whether pegvisomant treatment inhibits GH signaling in mice

doi: 10.1152/ajplung.1999.277.6.L1142 124 PostMBarsoumianASmithBT