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Treatment with SFN activates the NRF2 signaling pathway, mitigating oxidative stress injury and attenuating the inflammatory response associated with psoriasis
Major sources include Brazil nuts, seafood, lean meats, eggs, and whole grains, with their selenium content largely dependent on soil concentration and regional variability (124, 125)
Combination therapy with medications like phentermine/topiramate (Qsymia) or naltrexone/bupropion (Contrave) may benefit some patients, though evidence for combining these with GLP-1 agonists remains limited
Effectiveness: Moderate
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