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Boz only prescribes Tirzepatide because it is a dual agonist, targeting both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
The efficacy tradeoffs with semaglutide split dosing are smaller because there is no glucagon threshold concern
By calming both hunger intensity and reward driven eating, the regimen encourages more mindful eating and more stable calorie intake throughout the day
2019;708:1420 DOI: 10.1016/j.gene.2019.05.023 34
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