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The standard 2.5 mg starting dose was chosen precisely because it balances tolerability with efficacy for most people

Written informed consent for participation in this study was provided by the participants legal guardians/next of kin

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The LC-MS metabolite peaks were manually identified and integrated by EL-Maven (Version 0.11.0) by matching with a previously established in-house library 99

BALANCE Is Indefinitely Delayed The BALANCE Model (Better Approaches to Lifestyle and Nutrition for Comprehensive hEalth) was the planned permanent framework to waive the Part D weight-loss exclusion for participating plans