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The control HGF without the wash-out step ( black bars 2 ) presented higher indices than the levels of regular control HGF at both HGF doses (also see gray bars 3 with wash-out step)

Although the mechanisms underlying these effects remain largely unknown, they are assumed to at least in part rely on the ability of PPAR to decrease ectopic lipid deposition by stimulating adipocyte differentiation and fatty acid uptake 10,11,23

When supplementing, it's important to note that the Tolerable Upper Intake Level (UL) from supplements is 350 mg per day for adults