Gentile M, Offidani M, Vigna E, Corvatta L, Recchia AG, Morabito L, Morabito F, Gentili S (2015) Ixazomib for the treatment of multiple myeloma
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Activation of nuclear factor-B (NF-B) results in downstream pro-inflammatory cytokine release, such as tumor necrosis factor- (TNF-), interleukin (IL)-6, and IL-1, which amplify ROS-induced myocardial stress further promoting adverse remodeling, fibrosis, and myocardial dysfunction (Jia et al., 2018)
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