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Short-chain fatty acids (SCFAs) such as butyrate, a bacterial metabolite produced from dietary fibre, can directly trigger GLP-1 release by binding to the membrane receptor GPR43 (65)

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These sentiments and outcomes are echoed in the monthly pouch zoom forums where we occasionally hear personal testimonies from contented (and thinner) pouchees

It helps to know what you have tried before, what helped, and where progress tended to stall