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The present study observed reduced expression of 25-hydroxylase enzymes and 1--hydroxylase, vitamin D receptor, and increased expression of the 24-hydroxylase enzyme in the livers of HFD-fed mice
Peer review Peer review information Nature Metabolism thanks Florian Greten, Luisa Iommarini and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
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Conversely, patients who carry variants in hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, rs72613567) and mitochondrial amidoxime-reducing component 1 (MARC1, rs2642438) are more protected than the general population (48, 49)
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