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For example, platinum (IV) prodrugs activated by intracellular GSH have demonstrated enhanced tumor selectivity and reduced systemic toxicity in clinical trials
3 This new delivery system makes nutrients more stable and resistant to degradation from UV light or other stresses
At day 5 aggregates were gently collected, sieved through a reversible strainer and transferred into matrigel-coated plates with neural proliferation medium
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Accordingly, production of the endogenous antioxidant glutathione (GSH) by glial cells within the brain [8], particularly astrocytes [8,9,10], is a critical function, as most antioxidants are unable to cross the blood brain barrier
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