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GLP-1s (glucagon-like peptide-1 receptor agonists) mimic a hormone naturally produced in your gut
The reduced binding protein affinity also means more free IGF-1 LR3 remains available to interact with target tissues
Whilst gastritisinflammation of the stomach liningis not specifically listed as a recognised adverse effect in the Summary of Product Characteristics, Wegovy commonly causes gastrointestinal symptoms that may mimic gastric discomfort
Nordlund, J
Until supply issues have resolved, clinicians are being advised to avoid initiating people with type 2 diabetes on GLP-1 RAs
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