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Weight loss comes from an energy deficit roughly 7700 kcal under maintenance per kilogram of fat (about 3500 kcal per pound)

This reduces blood flow to superficial tissues, limiting the delivery of inflammatory cells and mediators to injury sites

Side effects at this stage are typically mild and intermittent for most patients

And for those already on semaglutide who want to understand related growth hormone peptides, resources on CJC-1295 and ipamorelin provide context on alternatives to sermorelin within the GH secretagogue class