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Graphical Abstract Similar content being viewed by others Introduction Obesity is an escalating global health issue

It has been noted that an inflammatory response is established due to the excessive production of prostaglandin E2, cytokines, and nitric oxide (NO) by macrophages and other inflammatory cells (68)

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Lacey checks your vital signs, takes your height, weight, and measurements, reviews or obtains labs, and gathers a full health history

Additionally, if the injection technique is suboptimalsuch as failing to allow the medication to reach room temperature before usethis may exacerbate local tissue irritation and increase the likelihood of itching