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The last day of the Vinita Aroda, MD, director of diabetes clinical research at Harvard Medical School, opened the session by describing the evolution of GLP-1s over the years, starting in 2005 with Exenatide BID, where patients saw about 2 pounds of weight loss and flattening 1 and continuing through 2019, where oral semaglutide showed that it could 2 Then came the combination tirzepatide [glucose-dependent insulinotropic polypeptide] and GLP-1 receptor agonist, which again has opened up a new wave of another unfolding, so to speak, said Aroda

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To understand what these supplements actually dobeyond marketing claimswe need to examine the individual compounds and their evidence bases

One example is the retatrutide injection kit: The substance contained in the kit is still in clinical development and is not authorised internationally