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421,422 Remarkably, GLP-1R activation in certain nuclei (such as the VTA, NAc, and vHP) elicits reductions in food intake and body weight without concurrent nausea responses
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Mol Metab 2021;46:101102.PubMed 3
In the latest Cochrane review of 12 placebo-controlled trials, supplementation with folic acid, vitamin B 6 , and vitamin B 12 either alone or in combination did not affect the risk for myocardial infarction and was associated with only a very small reduction in risk for stroke (RR, 0.90
Other health risks include: Pancreatitis: Some studies suggest a possible link between GLP-1s and inflammation of the pancreas, though the risk appears to be low
