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Semidehydroascorbate is reconverted to ascorbate in the cytosol by cytochrome b 5 reductase and thioredoxin reductase in reactions involving NADH and NADPH, respectively
The role of the carnitine system in human metabolism
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In breast cancer, CHAC1 overexpression promotes both proliferation and migration, while in ovarian cancer, its impact is primarily restricted to cell migration, with minimal effect on proliferation ( TP53, encoded by the TP53 gene and mutated in over 50% of human cancers, is essential for cell-cycle regulation and the induction of programmed cell death
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