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Most of them may not cause any serious harm, but wont produce any serious results either
The SURMOUNT-4 randomized clinical trial similarly identified mild to moderate gastrointestinal events as the most common adverse reactions (nausea [35.5%], diarrhea [21.1%], constipation [20.7%], and vomiting [16.3%]) (Aronne et al., 2024)
Genetic Predispositions and Individual Response Variation Not all patients respond equally to GLP-1 or GIP-receptor agonists
You rarely need all of it, and you cannot tell which component is doing anything
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