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The safest approach is to combine provider-guided treatment, lifestyle changes, education, and consistent follow-up. Florida Surgery and Weight Loss Center medical weight loss team Some patients may notice appetite changes within the first several weeks, while others may require more time and dose adjustment before seeing meaningful changes
Some patients who required insulin achieve good enough control with semaglutide to discontinue insulin entirely
The first is that your body gets used to the change, adapts to a slightly slower digestive speed, and is able to keep you regular throughout your natural cycles
In TRANSCEND-T2D-1 (type 2 diabetes): nausea 26.5%, diarrhea 22.8%, vomiting 17.6%, dysesthesia 4.4%