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Mechanistically, it activates Nrf2 and its nuclear translocation, thereby enhancing the expression of downstream antioxidant genes to relieve oxidative stress
In clinical trials, tirzepatide has shown substantial reductions in HbA1c and body weight, with effects varying by dose and patient population
We are losing around 20% of muscle mass, but that is not different from diets that restrict calorie intake
It thus ensures their proper function and activity
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