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Before taking this injection inform your doctor if you have liver or kidney problems, Leber's disease (nerve disease that leads to sudden, painless vision loss)

Metformin, commonly prescribed for type 2 diabetes, is known to reduce B12 absorption over time, as highlighted in MHRA safety updates

At the same time, more of your existing NAD+ gets consumed by enzymes like CD38 and PARPs, which are activated by things like inflammation, oxidative stress, and DNA damage

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If you suspect you have a deficiency or fall into one of these groups, consulting with a professional can help you decide if B12 shots are the right choice for you