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In addition, some studies do not clearly distinguish between taste and flavour, meaning that alterations in olfaction or oral somatosensation may be misattributed to gustatory dysfunction ( Accordingly, the current evidence is insufficient to conclude that GLP-1RAs produce a consistent and stable alteration in basic gustatory sensory function

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Semaglutide side effects are common, especially during the first month and after dose increases, but the vast majority are temporary

Usually resolve within hours

These findings suggest that GLP-1 RAs could play a crucial role in the management of HFpEF, particularly in patients with obesity, by targeting the underlying inflammatory processes and contributing to better overall cardiovascular outcomes