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If you have not been successful in losing weight through diet and exercise, your healthcare provider may recommend taking a weight-loss drug for treatment of obesity or overweight and weight-related comorbidities

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(Glucagon, like insulin, is one of the hormones that regulates blood sugar.) The shot, called retatrutide, is already looking more powerful than any drug on the market in this category, earning it the nickname "King Kong" from doctors and researchers working in diabetes and weight loss treatment