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Mass spectrometry-based microassay of 2 H and 13 C plasma glucose labeling to quantify liver metabolic fluxes in vivo
An emerging and highly promising strategy involves developing multi-target agonists that also engage the glucagon-like insulinotropic polypeptide receptor (GIPR) and/or the glucagon receptor (GCGR) [14, 15]
Originally developed for treatment of Type 2 diabetes (T2D), many patients reported appetite and weight reductions, and utilization soon skyrocketed for people with and without T2D
Similar findings were reported in a study that evaluated the effect of single and repeated grapefruit juice ingenstion on the oral plasma exposure of talinolol in humans
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