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We discovered that TAX6/Calcineurin serves as a key component in inhibiting GPCR signaling: while tax6 mutants were unable to generate pulsatile activity and reach exact adaptation in response to the natural stimulus diacetyl (Figs 3 and 4), their calcium dynamics following optogenetic activation was similar to wt worms (Fig 5)

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Limitations of Oral BPC-157 Despite its benefits, oral delivery has certain drawbacks: Lower systemic absorption: Only a fraction of the peptide survives digestion and reaches circulation

Motivation is provided by inflammatory signals from the injury

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