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You should not expect to see dramatic changes overnight

Cross-Trial Context# Retatrutide's 24.2% weight loss at 48 weeks appears numerically superior to semaglutide's 14.9% at 68 weeks, but several factors complicate direct comparison: Trial phase : Phase 2 trials often yield more favorable results than Phase 3 (smaller, more controlled populations) Treatment duration : Semaglutide data are at 68-104 weeks

What Do the Guidelines Recommend

But studies published in 2024 showed there was little to no increased risk of contracting thyroid cancer while on these drugs

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