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Ethinyl estradiol and 17-estradiol: pharmacokinetics, metabolism, and risk assessment

A 2007 study demonstrated that AHK-CU stimulated hair follicle elongation and dermal papilla cell proliferation while reducing apoptosis markers [1]

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The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting