Therefore, DPP-4 inhibitors may have pleiotropic effects
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The drug, Melanotan II, is an unlicensed and largely untested synthetic version of the peptide -melanocyte-stimulating hormone
To further confirm this observation, we transfected HepG2 cells with either scrambled siRNA or siRNA targeting GS overnight, followed by TNF challenge
Body weights were measured before treatment and then once a week till sacrificed
