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Effects of perfluorooctanoic acid exposure during pregnancy in the mouse
Conceptual Dose-Response Curve Microdosing discussions generally refer to the first category in this curve, where medication exposure is below the dose ranges evaluated in clinical trials
Tier 3 (same-day evaluation): Right-upper-quadrant pain radiating to the shoulder, severe abdominal pain, jaundice, signs of dehydration (orthostatic dizziness, dark urine, heart rate above 100 at rest), or inability to tolerate any oral fluids for 12 hours
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