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Elife 2 , e00499 (2013)
Notably, incubation of AX with L-cysteine (with the nonprotected-amino group) did not afford DKP, but mainly, the product corresponding to the aminolysis of the -lactam ring, which remained conjugated to the amino group of cysteine through an amide bond ( Figure S8 )
With this unforeseen side-effect, researchers at the University of Leeds and Novo Nordisk (the company that produces Semaglutide) conjectured that it can also be used for the treatment of obesity
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Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S
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