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Direct Flame Burn Studies Mice treated with BPC-157 cream showed reduced edema (swelling) at the burn site throughout the observation period

Comprehensive toxicology studies found no lethal dose even at extremely high levels (20 mg/kg intramuscularly in rats, equivalent to approximately 1,400 mg for a 155 pound human)

More direct evidence for GLP-1 modulating dopamine transmission comes from a study showing that a GLP-1 agonist also reduced phasic dopamine response in the VTA in rats (Konanur et al., 2020)