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It directly engages NF-kB signaling, the master inflammatory transcription factor governing expression of IL-6, TNF-alpha, IL-1beta, COX-2, and hundreds of related mediators

The study further revealed that the combination of AOD9604 and hyaluronic acid injections surpassed the effectiveness of either hyaluronic acid or AOD9604 alone [9]

Inflammation- and stress-response signaling research : Investigators track pathway markers, mediator expression, or tissue-response profiles in model systems that may include BPC-157 as a probe