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Nevertheless, a systematic assessment of their therapeutic applications, mechanisms, and clinical translation challenges in IMIDs remains lacking

A total of 11 female and 28 male participants were given 180 mg of curcumin daily

A double-blind randomized study

Some doctors may be open to exploring it if they feel the potential benefits outweigh the risks, while others may be hesitant due to the lack of clinical evidence specific to RA

In this context, even moderate increases in oxidative demand can favor conditions that increase mitochondrial electron leakage and ROS formation, particularly when respiratory reserve and redox-buffering capacity are reduced