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Reduced caloric intake combined with metabolic changes can cause fatigue, especially at the maximum dose
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Add bacteriostatic water slowly, directing the stream down the inside wall of the vial rather than onto the powder directly
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The authors were supported by the Agence Nationale de la Recherche (ANR-2011-BSV1-012-01 MLT2D and ANR-2011-META MELA-BETES), the Fondation de la Recherche Mdicale (Equipe FRM DEQ20130326503), Institut National de la Sant et de la Recherche Mdicale (INSERM) and Centre National de la Recherche Scientifique (CNRS)
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