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Both ipamorelin and CJC-1295 are short, lab-synthesized chains of amino acids
dual-agonist triple-agonist
Beyond pancreatic effects, GIP receptor agonism enhances peripheral insulin sensitivity, particularly in adipose tissue, where it promotes healthy white adipose tissue (WAT) expansion, facilitates dietary triglyceride clearance through increased lipoprotein lipase activity and adipose blood flow, and improves lipid buffering capacity [40]
The guidance emphasized post-marketing surveillance informed by pre-marketing safety signals, moving away from a rigid one-size-fits-all model
Antiemetics are not routinely recommended for GLP-1-associated nausea, but short-term use may be considered under medical supervision if symptoms are severe
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