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In mouse models, reduction of Aldh3a2 induced ferroptosis in leukemic cells and was synergistically lethal combined with the inhibitor of glutathione peroxidase 4 (GPX4) RSL3, whereas it was dispensable for normal hematopoiesis

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Retrieved August 17, 2018.

These symptoms typically resolve as your body equilibrates to the medication, but persistent or severe chills warrant immediate contact with your prescribing provider

Bianchi R, Cervellini I, Porretta-Serapiglia C, Oggioni N, Burkey B, Ghezzi P et al (2012) Beneficial effects of PKF275-055, a novel, selective, orally bioavailable, long-acting dipeptidyl peptidase IV inhibitor in streptozotocin-induced diabetic peripheral neuropathy