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Topical 10% zinc sulfate solution for treatment of melasma Dermatol Surg
That regulatory status is important for patients to understand, but it should be separated from the biological research
10.1002/clt2.12207 52
Injection site irritation occurs infrequently with proper technique
If standard doses are not tolerated, clinically appropriate alternatives might include slower titration (still within SmPC guidelines), switching to a different GLP-1 receptor agonist, considering other medication classes, enhancing diet/lifestyle support, or specialist review
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