Researchers found that HR488B (HDACi) induces cell cycle G0/G1 arrest and apoptosis through mitochondrial dysfunction, reactive oxygen species (ROS) generation, and accumulation of DNA damage, thereby specifically inhibiting the growth of CRC cells
This likely relates to the nitric oxide modulation and vasodilation effects of the peptide
Baseline renal function matters when evaluating any compound cleared by the kidneys, and is a standard part of any comprehensive pre-intervention assessment
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Acid or sour stomach belching constipation diarrhea stomach discomfort or upset Less common Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site Other side effects not listed may also occur in some patients
Benefits: collagen & elastin production, firmer skin, wound healing, reduced inflammation, and hair growth
