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DNA Repair (Amst) 6:265269 Fousteri M, Vermeulen W, van Zeeland AA, Mullenders LHF (2006) Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodelling and repair factors to stalled RNA polymerase II in vivo

doi:10.1016/S0076-6879(71)18006-8

Time-to-event analysis confirms these findings: Conclusions on the DEXACET trial This study shows that acetaminophen reduces the rate of delirium, possibly by reducing the use of opioid

Prior studies suggest that these taxa are biologically relevant in disease contexts including colitis-associated intestinal inflammation, vascular aging/endothelial dysfunction, metabolic dysfunction, or broader host inflammatory dysregulation, supporting their potential relevance to the present model.Citation 33 , Citation 34 , Citation 58-60 At the same time, direct evidence linking these specific taxa themselves to circadian rhythmicity remains limited, and therefore the rhythmic features emphasized here are derived primarily from our own data

Given the excellent safety profile observed in trials, longer protocols appear well-tolerated