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The system provided dual responsive release under low pH and high ROS

By activating GLP-1 receptors in the brain, semaglutide helps to increase the production of satiety hormones and reduce hunger signals, making it easier for individuals to adhere to a healthy eating plan

This dual action of reducing food intake and promoting satiety makes it a powerful tool in the fight against obesity and metabolic syndrome

However, concerns regarding the safety of such agents, in particular the increased risk of diabetic ketoacidosis (DKA) with SGLT2is, have restricted their widespread adoption in type 1 diabetes [15]

8,000 per session and require medical supervision