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The Institute for Clinical and Economic Review (ICER) analysis (2025) reaffirmed that even after price drops, GLP-1s consume a large share of pharmacy budgets, though at cost-effective levels relative to benefit ( [11] )
A recent meta-analysis suggested a decline with age and disease duration in the levels of glutamate and glutamine [17]
doi:10.1038/s41598-020-75334-9
Al-Chalabi A, van den Berg LH, Veldink J
The pleiotropic effects of sodium-glucose cotransporter-2 inhibitors: beyond the glycemic benefit
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