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Diabetes, 52(10), 2546-2553

Our testing has uncovered significant levels of an impurity that results from a chemical reaction between tirzepatide and B12

found that reduced CSF PLP concentrations may be a more sensitive indicator of vitamin B6-dependent epilepsy, especially vitamin B6-dependent epilepsy caused by mutations in PLPBP [12]

The elevated B12 appears to be a consequence of disease activity, likely resulting from increased production of B12-binding proteins by tumor cells or from liver involvement in the cancer process

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